Vacation rentals in Panama City, Panama

Carefully selected & verified rentals in Panama City, Panama
Check-in
26Jun2025Select date
Check-out
27Jun2025Select date
Rooms and Guests2 Guests, 1 Room
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281-300 out of 393
Sort by: high popularity
  • Price: low to high
  • Price: high to low
  • Guest rating: high to low
  • Popularity: high to low
Perfecto Apartamento En Panama
Map3.7 mi from City Centre1.2 mi from Panama Viejo Cathedral
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Boutique Atlapa Aparment Apartment Panama City
Map1.1 mi from City Centre200 yd from ATLAPA Conventions Center
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Cozy Apartment In The Heart Casco Viejo
Map3.1 mi from City Centre200 yd from Presidential Palace
FromUS$ 63 /nightSelect
Ph The Sands Apartments & Mall
Map2.6 mi from City Centre900 yd from Canal Museum of Panama
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Espectacular Apartamento Con Vista Al Mar
Map2.6 mi from City Centre900 yd from Canal Museum of Panama
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Amazing 2Br In Wanders And Yoo
Map1700 yd from City Centre1300 yd from Coastal Beltway
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Modern 2Br Apt Near Trendy Via Argentina & Metro
Map1100 yd from City Centre1500 yd from Coastal Beltway
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Mango House
Map14.1 mi from City Centre
FromUS$ 28 /nightSelect
The Colonial Condo Amplio & Familiar En Casco
Map3.2 mi from City Centre700 yd from Canal Museum of Panama
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Beautiful And Spacious Apartment In Cinta Costera N#10
Map1.8 mi from City Centre900 yd from Coastal Beltway
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Elegant Spacious Apt On The Cinta Costera N#9
Map1.8 mi from City Centre900 yd from Coastal Beltway
FromUS$ 294 /nightSelect
Cute Loft Infront Of The Catedral In Casco Antiguo
Map3.1 mi from City Centre200 yd from Presidential Palace
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Amazing Experience In Casco Viejo Historical Site 3
Map3.1 mi from City Centre400 yd from Presidential Palace
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Villas La Fontana Amplias Apartasuite-Piscina 204
Map3.1 mi from City Centre300 yd from Presidential Palace
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Hermoso Apartamento Para Sentirse Como En Casa
Map1.0 mi from City Centre300 yd from El Ingenio
FromUS$ 61 /nightSelect
Unique Yoo Luxury 2-Bedroom 3-Story Loft
Map1.3 mi from City Centre300 yd from Coastal Beltway
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Ocean View Penthouse
Map1.6 mi from City Centre800 yd from Coastal Beltway
FromUS$ 600 /nightSelect
Apto Lebaron
Map1200 yd from City Centre1.1 mi from Coastal Beltway
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Centrico
Map1.4 mi from City Centre700 yd from Coastal Beltway
FromUS$ 34 /nightSelect
Bello Apartamento En Tocumen - Mystic Village
Map8.4 mi from City Centre
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Flexible Price Range for Vacation Homes in Panama City

From cozy retreats to luxury villas – Find the ideal stay for every budget

⬆️ The highest price
US$ 1 064
⬇️ The lowest price
US$ 16
đź’¸ Average price for
Apartments
US$ 122

Top vacation homes in Panama City

Based on guest reviews from the past 12 months

Charming Boutique Retreats:
Amazinn Places Hotel Boutique Casa Marichu
Convenience Near the Airport:
Lilia House 15 Minutos Aeropuerto
Stylish Coastal Apartments:
Boutique Apartments Panama Coco Del Mar
Scenic City Views:
Impressive City View Apartment Marbella - Ph Quartier Marbella
Historical Vibes in Casco Viejo:
Casa Lourdes By Acomodo Casco Viejo
Ideal for Families:
Impressive Family City View Apt B - Ph Quartier Marbella
Modern Luxuries:
Yoo Panama
Penthouse Experiences:
Amazinn Places Rooftop And Jacuzzi IV
Romantic Getaways:
Amazinn Places Casco Viejo Jacuzzi, Adults Only
Cultural Heritage Stays:
Amazing Experience In Casco Viejo Historical Site1

How to get to Panama City

Explore local transportation options with ease

Airports
Tocumen International (PTY)
Paitilla (PAC)

Vacation Rentals Overview in Panama City

This guide provides essential insights into vacation rentals in Panama City, covering evaluated properties including prices, local fees, and proximity to key attractions for informed decision-making.

Typical nightly rates range from $50 to $200.

There are approximately 100 vacation rental properties available.

Peak travel seasons are December to April.

Local taxes and fees total around 10%.

Most rentals are within 3 miles of major attractions like Casco Viejo.

Check-in
26Jun2025Select date
Check-out
27Jun2025Select date
Rooms and Guests2 Guests, 1 Room