Vacation rentals in Panama City, Panama

Carefully selected & verified rentals in Panama City, Panama
Check-in
07Feb2026Select date
Check-out
08Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Panama City boasts iconic spots like the Panama Canal, Casco Viejo, and the Amador Causeway. Enjoy vibrant nightlife at venues like Ocean Club Casino or relax on the sands of Playa Veracruz. You'll find amazing options from luxury hotels near the canal with stunning skyline views, to boutique hotels in Casco Viejo with unique architecture. This selection is carefully chosen based on excellent amenities and guest reviews. Book your stay early, as the best deals tend to go fast, especially during the Carnival season, and consider using public transport for easy city access.
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Best Location - Spacious And Fancy Apt Panama City
Map3.0 mi from City Centre200 yd from Presidential Palace
FromUS$ 250 /nightSelect
Amazinn Places Teatro Nacional Panama City
Map3.0 mi from City Centre200 yd from Presidential Palace
FromUS$ 77 /nightSelect
Blue Dream In San Francisco
Map800 yd from City Centre1700 yd from ATLAPA Conventions Center
FromUS$ 120 /nightSelect
Apartamento En El Corazon De Casco Viejo Panama 12
MapHistoric Casco Viejo neighborhood100m
  • City views from private balcony
  • On-site American cuisine restaurant
  • Outdoor dining area available
  • City views
  • Outdoor dining
  • Restaurant on-site
Hotel offering modern amenities in vibrant historic district
FromUS$ 78 /nightSelect
Villas La Fontana Amplia Apartasuite- Piscina 102
Map3.1 mi from City Centre300 yd from Presidential Palace
FromUS$ 180 /nightSelect
Amazinn Places Casco Viejo Unique Desing And Pool III
MapHistoric Casco Viejo neighborhood0m
  • Year-round outdoor swimming pool
  • Solarium with sun loungers
  • City views from private balcony
  • Outdoor pool
  • Solarium
  • City views
Contemporary hotel with stylish designs and amenities
FromUS$ 276 /nightSelect
Wanders & Yoo
Map1700 yd from City Centre1300 yd from Coastal Beltway
FromUS$ 484 /nightSelect
Amazinn Places Casco Viejo Unique Desing And Pool II
Map3.0 mi from City Centre200 yd from Presidential Palace
FromUS$ 110 /nightSelect
Amazinn Places Rooftop And Design Pool III
MapVibrant Casco Viejo neighborhood0.5km
  • Stunning rooftop pool area
  • Solarium with sun loungers
  • Comfortable design rooms
  • Rooftop pool
  • Solarium
  • Garden access
Stylish hotel with rooftop pool and leisure amenities
FromUS$ 129 /nightSelect
Boutique Apartments Panama Atlapa
Map1.1 mi from City Centre200 yd from ATLAPA Conventions Center
FromUS$ 35 /nightSelect
Amazinn Places Casco Viejo Casa Espanola
MapHistoric Casco Viejo neighborhood0.5km
  • Outdoor pool and jacuzzi available
  • Spacious rooms with fully equipped kitchen
  • Pet-friendly and non-smoking property
  • Outdoor pool
  • Jacuzzi
  • Fully equipped kitchen
Hotel with modern amenities in historic district
FromUS$ 110 /nightSelect
Amazinn Places Casco Viejo Pool And Rooftop V
Map3.2 mi from City Centre400 yd from Presidential Palace
FromUS$ 81 /nightSelect
Maison Boheme - La Manzana Panama
Map3.2 mi from City Centre700 yd from Canal Museum of Panama
FromUS$ 61 /nightSelect
R.4-4 Lindo Estudio Ejecutivo En Area Turistica.
Map1800 yd from City Centre1600 yd from Coastal Beltway
FromUS$ 66 /nightSelect
Yoo Luxury Tower Front Sea View Apartment
Map1.3 mi from City Centre300 yd from Coastal Beltway
FromUS$ 158 /nightSelect
Amazinn Places Private Splash Pool And Relaxing Sound Of Sea
Map3.2 mi from City Centre500 yd from Presidential Palace
FromUS$ 581 /nightSelect
Business Condo Suite 1Br
Map3.7 mi from City Centre1.2 mi from Panama Viejo Cathedral
FromUS$ 128 /nightSelect
Casa Lourdes By Acomodocasco Viejo-Large Groups!
Map3.1 mi from City Centre300 yd from Presidential Palace
FromUS$ 82 /nightSelect
Impressive City View Apartment Marbella - Ph Quartier Marbella
Map1.1 mi from City Centre800 yd from Coastal Beltway
FromUS$ 113 /nightSelect
Amazinn Places Rooftop And Jacuzzi IV
MapNear Canal Museum of Panama300m
  • Rooftop terrace with jacuzzi
  • Pets allowed for guests
  • Fully equipped kitchen available
  • Rooftop terrace
  • Hot tub
  • Air conditioning
Hotel featuring rooftop and jacuzzi in vibrant district
FromUS$ 104 /nightSelect

Flexible Price Range for Vacation Homes in Panama City

From cozy retreats to luxury villas – Find the ideal stay for every budget

⬆️ The highest price
US$ 719
⬇️ The lowest price
US$ 17
đź’¸ Average price for
3-star hotels
US$ 74
Apartments
US$ 129

Top vacation homes in Panama City

Based on guest reviews from the past 12 months

How to get to Panama City

Explore local transportation options with ease

Airports
Tocumen International Airport (PTY)
Albrook "Marcos A. Gelabert" International Airport (PAC)

FAQs about Panama City rentals

Get answers to common questions and plan your adventure smoothly

Which neighborhoods in Panama City are best for vacation rentals near major attractions?
Casco Viejo and Avenida Balboa are popular neighborhoods for vacation rentals, both within 3 km of key landmarks like the Panama Canal and Biomuseo.
What vacation rentals in Panama City offer unique views?
Properties like Yoo Panama and Signature Point Bella Vista provide stunning city and ocean views, ideal for guests seeking picturesque scenery.
What are the best vacation rentals for couples in Panama City?
Couples may enjoy options like Casa La Costa By Wynwood House, which offer romantic settings and amenities, or the Luxurious Rooftop and Jacuzzi properties for a special stay.

Vacation Rentals Overview in Panama City

This guide provides essential insights into vacation rentals in Panama City, covering evaluated properties including prices, local fees, and proximity to key attractions for informed decision-making.

Typical nightly rates range from $50 to $200.

There are approximately 100 vacation rental properties available.

Peak travel seasons are December to April.

Local taxes and fees total around 10%.

Most rentals are within 3 miles of major attractions like Casco Viejo.

Other cities in Panama

Check-in
07Feb2026Select date
Check-out
08Feb2026Select date
Rooms and Guests2 Guests, 1 Room